[WARNING: Before making any changes to your diet or therapy programs, check with your doctor who is authorized to diagnose and treat symptoms and disease. The following is for discussion purposes only and is not a recommendation.]

Another round of studies proves aspirin, or equivalent pain medication, may be cheaper than burning through cash if you are currently swallowing expensive Glucosamine supplements for control of your joint pain.

As all doctors know all too well, it is difficult to get around the PLACEBO effect See End Note 1 when discussing and trying to measure such things as pain levels. According to a recent statement from Dr. Mirkin, M.D., there exist no reliable studies able to show that Glucosamine performs better for arthritic pain than does aspirin.

What is interesting to note is that one study cited by Dr. Mirkin DOES SHOW positive results for growing a component of cartilage called aggrecan and that may be promising, but it is too early to make such a claim.

Mirkin explains, “…aggrecan, [is] the part of cartilage that allows cartilage to swell and shrink, acting like a shock absorber to help protect your knees from the trauma of running and walking.” However, that research was on cells in a TEST TUBE, not in people. In other words, it may be too early to make any reliable scientific claim of experiencing aggrecan growth and cartilage growth in the knees of people and not merely in test tubes.

The fact that aggrecan was grown in test tubes may lead people to assume and experiment in their own bodies, especially those who are living with joint pain. Those with joint pain may be all too eager to chow down on Glucosamine, just in case it might have some positive effects. After all, as most people typically, but incorrectly believe, “What harm can a simple supplement do?”

Remind yourself that a supplement is a pharmaceutical and all pharmaceuticals should be expected to have side effects.

Further, as I repeatedly warn throughout my Nuggets appearing on these “Anti-aging” pages, when it comes to the human body, especially with supplements, there is no free ride. By jacking up the concentrations of dosages of one particular supplement you may impact the delicate balance to which the body strives in its quest to continuously optimize a person’s health. So, be careful with supplements despite all the glowing testimonials of people who may swear by it. And this includes Glucosamine.


Mirkin mentions another study that shows, “glucosamine can block the effects of insulin, causing blood sugar levels to rise increasing likelihood of suffering the side effects of diabetes in susceptible people.” See End Note 2

By the way…

IF YOU ARE STRUGGLING WITH JOINT PAIN, you may want to read a few of Dr. McDougall’s studies. Simply visit his website at the following link. In the search box type in whatever chronic disease you wish to treat. If it is joint pain, type in “joint pain”. Or also enjoy his free information about other search terms such as arthritis, rheumatism, breast cancer, etc. Take any of his studies to your doctor and have a great discussion… Dr. McDougall’s search box can be accessed by clicking here.   


  1. PLACEBO EFFECT: the effect a person’s conscious or subconscious wishes and expectations have on the actual outcomes and results when taking medications.  This is a very significant reason why testimonials, anecdotes of improvements, are often unreliable as indicators of actual outcomes. People may claim to be experiencing positive results when, if the measurements were available or performed accurately, there is no physical changes. “It’s only all in their head”, is an adage that applies to many testimonials, (anecdotal), claims until backed by hard, reliable, unbiased studies.
  2. “Glucosamine and Chondroitin Sulfate for Arthritic Pain” By Dr. Gabe Mirkin, M.D., FITNESS AND HEALTH NEWSLETTER. Oct. 23, 2017.